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1

Role of the N-terminus in human 4-hydroxyphenylpyruvate dioxygenase activity

Feng, An-Ning, Huang, Chih-Wei, Lin, Chi-Huei, Chang, Yung-Lung, Ni, Meng-Yuan, Lee, Hwei-Jen

Journal:

Journal of Biochemistry

Année:

2019

Langue:

english

Fichier:

PDF, 4.15 MB

english, 2019

2

A Kinetic Analysis of the Endogenous Lactate Dehydrogenase Activity of Duck Lens ε-Crystallin in Reverse Micelles

Hwei-Jen Lee, Gu-Gang Chang

Journal:

Journal of Colloid and Interface Science

Année:

1998

Langue:

english

Fichier:

PDF, 169 KB

english, 1998

3

Equilibrium protein folding-unfolding process involving multiple intermediates

Hui-Chih Hung, Yu-Hou Chen, Guang-Yaw Liu, Hwei-Jen Lee, Gu-Gang Chang

Journal:

Bulletin of Mathematical Biology

Année:

2003

Langue:

english

Fichier:

PDF, 302 KB

english, 2003

4

The role of arginine residues in substrate binding and catalysis by deacetoxycephalosporin C synthase

Sarah J. Lipscomb, Hwei-Jen Lee, Mridul Mukherji, Jack E. Baldwin, Christopher J. Schofield, Matthew D. Lloyd

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 160 KB

english, 2002

5

The kinetic properties of various R258 mutants of deacetoxycephalosporin C synthase

Hwei-Jen Lee, Young-Fung Dai, Chia-Yang Shiau, Christopher J. Schofield, Matthew D. Lloyd

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 215 KB

english, 2003

6

Monomeric molten globule intermediate involved in the equilibrium unfolding of tetrameric duck δ2-crystallin

Hwei-Jen Lee, Shang-Way Lu, Gu-Gang Chang

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 508 KB

english, 2003

7

Guanidine hydrochloride induced reversible dissociation and denaturation of duck δ2-crystallin

Hwei-Jen Lee, Gu-Gang Chang

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 858 KB

english, 2000

8

Kinetic comparison of caiman ε-crystallin and authentic lactate dehydrogenases of vertebrates

Shyh-Horng Chiou, Hwei-Jen Lee, Shih-Ming Huang, Gu-Gang Chang

Journal:

The Protein Journal

Année:

1991

Langue:

english

Fichier:

PDF, 520 KB

english, 1991

9

Substitution of residues at the double dimer interface affects the stability and oligomerization of goose δ-crystallin

Chih-Wei Huang, Chih-Chao Tseng, Ya-Huei Chen, Yu-Hou Chen, Wei-Yuan Chou, Hwei-Jen Lee

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 785 KB

english, 2009

10

10.1038/29575

Schofield, Christopher J., Andersson, Inger, Valegård, Karin, van Scheltinga, Anke C. Terwisscha, Lloyd, Matthew D., Hara, Takane, Ramaswamy, S., Perrakis, Anastassis, Thompson, Andy, Lee, Hwei-Jen, B

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 512 KB

english, 1998

11

Fluorescence studies on the dissociation and denaturation of pigeon liver malic enzyme

Hwei-Jen Lee, Yee-Hsiung Chen, Gu-Gang Chang

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Année:

1988

Langue:

english

Fichier:

PDF, 1.66 MB

english, 1988

12

Purification and characterization of the cytosolic NADP+-dependent malic enzyme from human breast cancer cell line

Gu-Gang CHANG, Jehng-Kang WANG, Ter-Mei HUANG, Hwei-Jen LEE, Wei-Yuan CHOU, Ching-Liang MENG

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 740 KB

english, 1991

13

The Effect of Cysteine Mutations on Recombinant Deacetoxycephalosporin C Synthase from S. clavuligerus

Hwei-Jen Lee, Matthew D. Lloyd, Karl Harlos, Christopher J. Schofield

Journal:

Biochemical and Biophysical Research Communications

Année:

2000

Langue:

english

Fichier:

PDF, 45 KB

english, 2000

14

Active Site Mutations of Recombinant Deacetoxycephalosporin C Synthase

Hwei-Jen Lee, Christopher J. Schofield, Matthew D. Lloyd

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 52 KB

english, 2002

15

pH-Induced Reversible Dissociation of Tetrameric Duck Lens Delta-Crystallin

GU-GANG CHANG, HWEI-JEN LEE, RUE-HUAN CHOW

Journal:

Experimental Eye Research

Année:

1997

Langue:

english

Fichier:

PDF, 465 KB

english, 1997

16

Studies on the active site of deacetoxycephalosporin C synthase

Matthew D Lloyd, Hwei-Jen Lee, Karl Harlos, Zhi-Hong Zhang, Jack E Baldwin, Christopher J Schofield, John M Charnock, C.David Garner, Takane Hara, Anke C Terwisscha van Scheltinga, Karin Valegård, Jen

Journal:

Journal of Molecular Biology

Année:

1999

Langue:

english

Fichier:

PDF, 726 KB

english, 1999

17

Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS)

Hwei-Jen Lee, Matthew D. Lloyd, Karl Harlos, Ian J. Clifton, Jack E. Baldwin, Christopher J. Schofield

Journal:

Journal of Molecular Biology

Année:

2001

Langue:

english

Fichier:

PDF, 419 KB

english, 2001

18

Kinetic mechanism of the cytosolic malic enzyme from human breast cancer cell line

Gu-Gang Chang, Ter-Mei Huang, Jehng-Kang Wang, Hwei-Jen Lee, Wei-Yuan Chou, Ching-Liang Meng

Journal:

Archives of Biochemistry and Biophysics

Année:

1992

Langue:

english

Fichier:

PDF, 620 KB

english, 1992

19

Quaternary structure of pigeon liver malic enzyme

Hwei-Jen Lee, Gu-Gang Chang

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 416 KB

english, 1990

20

Different roles of p53 in the regulation of DNA damage caused by 1,2-heteroannelated anthraquinones and doxorubicin

Yung-Lung Chang, Hwei-Jen Lee, Shu-Ting Liu, Yu-Sheng Lin, Tsung-Chih Chen, Tsai-Yuan Hsieh, Hsu-Shan Huang, Shih-Ming Huang

Journal:

The International Journal of Biochemistry & Cell Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2011

21

Distinct interactions of αA-crystallin with homologous substrate proteins, δ-crystallin and argininosuccinate lyase, under thermal stress

Ya-Huei Chen, Ming-Ting Lee, Yu-Wen Cheng, Wei-Yuan Chou, Chung-Ming Yu, Hwei-Jen Lee

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 880 KB

english, 2011

22

α-Crystallin protects human arginosuccinate lyase activity under freeze–thaw conditions

Yi-Yu Wei, Chih-Wei Huang, Wei-Yuan Chou, Hwei-Jen Lee

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 769 KB

english, 2012

23

Critical role of tryptophanyl residues in the conformational stability of goose δ-crystallin

Hwei-Jen Lee, Young-Hsang Lai, Yu-Ting Huang, Chih-Wei Huang, Yu-Hou Chen, Gu-Gang Chang

Journal:

Experimental Eye Research

Année:

2006

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2006

24

Monitoring protein conformational changes by quenching of intrinsic fluorescence

Gu-Gang Chang, Hwei-Jen Lee

Journal:

Journal of Biochemical and Biophysical Methods

Année:

1984

Langue:

english

Fichier:

PDF, 238 KB

english, 1984

25

Kinetic Refolding Barrier of Guanidinium Chloride Denatured Goose δ-Crystallin Leads to Regular Aggregate Formation

Yin, Fon-Yi, Chen, Ya-Huei, Yu, Chung-Ming, Pon, Yu-Chin, Lee, Hwei-Jen

Journal:

Biophysical Journal

Année:

2007

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2007

26

Structure-Based Drug Design of a Novel Family of PPARγ Partial Agonists: Virtual Screening, X-ray Crystallography, and in Vitro/in Vivo Biological Activities

Lu, I-Lin, Huang, Chien-Fu, Peng, Yi-Hui, Lin, Ying-Ting, Hsieh, Hsing-Pang, Chen, Chiung-Tong, Lien, Tzu-Wen, Lee, Hwei-Jen, Mahindroo, Neeraj, Prakash, Ekambaranellore, Yueh, Andrew, Chen, Hsin-Yi,

Journal:

Journal of Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 387 KB

english, 2006

27

Caffeic acid phenethyl ester induces E2F-1-mediated growth inhibition and cell-cycle arrest in human cervical cancer cells

Hsu, Tzu-Hui, Chu, Chin-Chen, Hung, Mei-Whey, Lee, Hwei-Jen, Hsu, Hsien-Jun, Chang, Tsu-Chung

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 599 KB

english, 2013

28

The effect of N-terminal truncation on double-dimer assembly of goose δ-crystallin

Lee, Hwei-Jen, Lai, Young-Hsang, Wu, Su-Ying, Chen, Yu-Hou

Journal:

Biochemical Journal

Année:

2005

Langue:

english

Fichier:

PDF, 722 KB

english, 2005

29

Chemical mechanism of the endogenous argininosuccinate lyase activity of duck lens δ2-crystallin

WU, Chi-Yue, LEE, Hwei-Jen, WU, Shih-Hsiung, CHEN, Shui-Tein, CHIOU, Shyh-Horng, CHANG, Gu-Gang

Journal:

Biochemical Journal

Année:

1998

Langue:

english

Fichier:

PDF, 478 KB

english, 1998

30

Functional Analysis of VDR Gene Mutation R343H in A Child with Vitamin D-Resistant Rickets with Alopecia

Tseng, Min-Hua, Huang, Shih-Ming, Lo, Fu-Sung, Huang, Jing-Long, Cheng, Chih-Jen, Lee, Hwei-Jen, Lin, Shih-Hua

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 2.19 MB

english, 2017

31

The Catalytic Roles of P185 and T188 and Substrate-Binding Loop Flexibility in 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase from Comamonas testosteroni

Hwang, Chi-Ching, Chang, Yi-Hsun, Lee, Hwei-Jen, Wang, Tzu-Pin, Su, Yu-Mei, Chen, Hsin-Wei, Liang, Po-Huang, Permyakov, Eugene A.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 3.34 MB

english, 2013

32

Magnolol ameliorates pneumonectomy and monocrotaline-induced pulmonary arterial hypertension in rats through inhibition of angiotensin II and endothelin-1 expression

Chang, Hung, Chang, Cheng-Yi, Lee, Hwei-Jen, Chou, Ching-Yu, Chou, Tz-Chong

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2018

33

Whole-exome sequencing detects mutations in pediatric patients with atypical hemolytic uremic syndrome in Taiwan

Tseng, Min-Hua, Tsai, Jeng-Daw, Tsai, I-Jung, Huang, Shih-Ming, Huang, Jing-Long, Fan, Wen-Lang, Lee, Hwei-Jen, Wu, Tai-Wei, Lin, Shih-Hua

Journal:

Clinica Chimica Acta

Année:

2019

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2019

34

Role of the N-terminus in human 4-hydroxyphenylpyruvate dioxygenase activity

Feng, An-Ning, Huang, Chih-Wei, Lin, Chi-Huei, Chang, Yung-Lung, Ni, Meng-Yuan, Lee, Hwei-Jen

Journal:

Journal of Biochemistry

Année:

2019

Fichier:

PDF, 4.15 MB

2019